Voltage-Gated Ion Channels as Drug Targets. Hugo Kubinyi и др.
- Тип: Текст PDF
- Авторы:
- Издательство: John Wiley & Sons Limited(2019)
- ISBN: 9783527607747
- Страниц: 493
- Язык: Английский
- Жанры: Научно-популярная литература
- Описание
- Фрагмент
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.