Pharmaceutical Amorphous Solid Dispersions. Группа авторов
- Тип: Текст PDF
- Автор:
- Издательство: John Wiley & Sons Limited(2018)
- ISBN: 9781118901380
- Страниц: 505
- Язык: Английский
- Жанры: Органическая химия
- Описание
- Фрагмент
Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world
