Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants. Yvonne Will и др.
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- Тип: Текст PDF
- Авторы:
- Издательство: John Wiley & Sons Limited(2019)
- ISBN: 9781119329732, 978-5-04-469859-8
- Страниц: 812
- Язык: Английский
- Описание
- Фрагмент
Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria